New MR imaging of CISS

CISS: Constructive Interference in Steady State


                

Right internal carotid angiogram (frontal view) Left internal carotid angiogram (frontal view)




MRA (frontal view)

          
CISS images (axial views): Small internal carotid arteries and moyamoya vessels are visualized.

Catheter cerebral angiography and MR angiography visualize blood flow in the arteries. In moyamoya disease, major cerebral arteries become stenotic and then blood flow within them reduces. It is rare to visualize the arteries themselves (arterial structures). Brain is surrounded by cerebrospinal fluid. CISS imaging does not visualize blood flow but the arterial structures such as cerebral arteries running within the cerebrospinal fluid and moyamoya vessels in the base of the brain. CISS imaging can provide high resolution structural information. Clinically, MR angiography is more useful than CISS imaging, but the latter helps to understand the clinical status because it shows the changes of the arterial structures, not blood flow itself. MR angiography usually overestimates the steno-occlusive changes of the cerebral arteries and underestimate moyamoya vessels. CISS imaging can supplement the defects of MR angiography in the clinical setting.


Reference


1. Komiyama M, Ishiguro T, Nishikawa M, et al: Constructive interference in steady state imaging of moyamoya disease. Neurol Med Chir (Tokyo) 42:11-17, 2002 [Abstract]